Is there a safe way to remove /index.php?

[[chrisB]]

Editing the QueryString.php file to remove 'index.php' causes an issue with missing css/images.

I'm wondering if there's a safe alternative way of achieving this?

Home URL: mydomain.com instead of mydomain.com/index.php

If there was a way to remove the index.php part just from the breadcrumb, I could replace the menu button using a menu editor mod. I know I am being quite fussy, but it's just my preference really.

When I visit my test install: https://cloudownload.co.uk/test/

I can visit without the index.php part, but the breadcrumb shows it which is why I am curious if there could be an alternative way aside from the QueryString.php file that seems to break things for first time guests.